The mitochondrial T16189C polymorphism is associated with coronary artery disease in Middle European populations.
BackgroundThe pivotal role of mitochondria in energy production and free radical generation suggests that the mitochondrial genome could have an important influence on the expression of multifactorial age related diseases.Substitution of T to C at nucleotide position 16189 in the hypervariable D-loop of the control region (CR) of mitochondrial DNA